Glioblastoma multiforme is the most common and aggressive type of primary brain tumor. Despite advances in surgical techniques, therapies, and radiotherapies, the prognosis for this type of pathology remains poor. There is however a small percentage of patients affected by glioblastoma multiforme who survive 3 years or longer. Also, there are very few rare cases, such as the two we are describing here, where patients have survived decades after surgical resection of the glioma. To our knowledge, these are some of the longest surviving patients (more than 21 years) in the literature whose initial diagnosis was glioblastoma and anaplastic astrocytoma, and who are living an independent meaningful life.

Longest Survival In Malignant Brain Tumor